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Although our sample size is not enough to
2024-03-19
Although our sample size is not enough to conclude that there is no great genetic variation of the AR gene in most New World monkeys, it would be reasonable to state that the microsatellite region in the exon 1 of the androgen receptor gene of New World monkeys (platyrrhine) is relatively shorter th
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Protease Inhibitor Cocktail (EDTA-Free, 100X in DMSO) austra
2024-03-19
Recently, rather than predicting categorical variables as in classification, several studies begin to estimate continuous clinical variables from Protease Inhibitor Cocktail (EDTA-Free, 100X in DMSO) australia images. Therefore, instead of classify a subject into binary or multiple pre-determined c
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br Materials and methods br Results br Discussion
2024-03-19
Materials and methods Results Discussion Competing financial interests Acknowledgements The work was partially supported by grants from the National Natural Science Foundation of China (Grant no. 31530053 and 31401424) and National Science and Technology Support Plan (Grant no. 2013BA
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In fact serotonin is a major modulator of dopaminergic
2024-03-19
In fact, serotonin is a major modulator of dopaminergic (DA) neuronal activity through the 5-HT2C receptor. Studies have shown that the selective 5-HT2C receptor agonist Ro60-0175 blocks the burst-firing of mesolimbic DA neurons, which project from the ventral tegmental area (VTA) to the nucleus acc
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Adenosine is a ubiquitous homeostatic substance released fro
2024-03-19
Adenosine is a ubiquitous homeostatic substance released from most cells, including neurons and glias. Endogenous adenosine acts at four principal G-protein-associated receptor subtypes: A1, A2a, A2b and A3 (Ralevic and Burnstock, 1998). The stimulation of adenosine receptors by extracellular adenos
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The scattering operators associated to are defined
2024-03-19
The scattering operators associated to are defined as follows: for any and , , , there exists a unique solution to the following equation such that Then the scattering operator is defined by Here is an elliptic pseudodifferential operator of order , which is conformally covariant on the boundary.
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In an insightful essay Heryanto writes that language is a
2024-03-19
In an insightful essay, Heryanto (1990, 40) writes that language is “a phenomenon expressing the particular history of a society” that did not exist in many parts of the world. “Language is not a universal category or cultural activity. Though it may sound odd, not all people have a language in the
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In this study we make the
2024-03-19
In this study, we make the first simultaneous recordings of Cilostazol release in multiple brain regions at a temporal resolution less than 1 s. One of the most striking findings is that acetylcholine release has a remarkably similar temporal profile in the mPFC and dHPC, suggesting a coordinated ac
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Axl which belongs to the Tyro Axl
2024-03-18
Axl, which belongs to the Tyro-Axl-Mer (TAM) family of RTKs, has been reported to regulate a variety of physiological processes including cell survival, proliferation, migration and adhesion, through the activation of the phosphoinositide 3-kinase (PI3K)/V-akt murine thymoma viral oncogene homolog (
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br Results br Discussion Both
2024-03-18
Results Discussion Both ATM and ATR are key regulators of the cellular response to DSBs, yet how exactly they function in concert is not well understood. Recent studies revealed that ATM is required for the resection of DSBs (Jazayeri et al., 2006, Myers and Cortez, 2006), a process necessary
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TLX may promote survival and prevent apoptosis
2024-03-18
TLX may promote survival and prevent apoptosis in NB MLN 9708 receptor [12]. Here, we ask whether the survival-promoting effects of TLX are mediated by Apoptosis Signal-regulating Kinase-1 (ASK1, MAP3K5). ASK1 is a member of the Mitogen-Activated Protein (MAP) kinase family and it preferentially ac
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Bioavailability has been defined as the amount of
2024-03-18
Bioavailability has been defined as the amount of a drug given by any route, other than intravenously, that reaches general circulation and is available at the site of action [86]. The low bioavailability observed with the initial intravaginal devices (16%) was attributed to the melting point of the
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Enhanced arginase activity and the
2024-03-18
Enhanced arginase activity and the resultant decreases in L-arginine levels can also impair T cell mediated immune function and allow tumor growth by limiting the supply of L-arginine needed for the formation of cytotoxic levels of NO by iNOS [10]. Increased arginase expression/activity may also lim
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br Acknowledgment This study was supported
2024-03-18
Acknowledgment This study was supported by Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research (KAKENHI) [grant number 15K15031]. Introduction Glioma is the leading malignancy of astrocyte origin in the brain. The most aggressive, invasive, and destructive glioma
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br Methodology br Antibiotics in
2024-03-18
Methodology Antibiotics in lakes Antibiotic resistance genes in lakes Perspectives of study on L-NMMA citrate australia and ARGs in lakes Conclusion This paper systematically reviewed the distribution of antibiotics and ARGs in global lakes. A total of 57 antibiotics reported at leas
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